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(More customer reviews)Hyphenation: Hype and Fascination
Edited by
U.A.Th. Brinkman , Department of Analytical Chemistry, Free University Amsterdam, The Netherlands
Description
Today, we all know that the combination of aconventional injection procedure, a single analytical column and aselective detector often does not suffice to recognize and quantify allanalytes of interest in a sample. During the eighties, the use ofmultidimensional approaches slowly began to make headway to help solve themany, and often complex, problems concerning the provisionalidentification, or confirmation of the presence, of analytes of interest,the design of separation systems with a considerably improved separationefficiency, and the generally felt need to incorporate the samplepreparation in the total analytical procedure.
Two major branchesemerged - hyphenation, which is often defined as the on-line combination ofa separation technique and a spectroscopic detection device which providesstructural information, and coupled-column techniques. Sometimeshyphenation is used to describe both of these branches, a practice that hasalso been followed when selecting the title of the present volume.
Gradually the glamour of hyphenation began to be recognised, and thehype and fascination were born.
Audience
For analytical chemists,biochemists, clinical chemists and all those who are concerned with theseparation and identification of mixtures or compounds in mixtures.
Contents
Preface (U.A.Th. Brinkman). Solid-phase extraction: methoddevelopment, sorbents, and coupling with liquid chromatography (M.-C.Hennion). Membrane-based sample preparation coupled on-line tochromatography or electrophoresis (N.C. van de Merbel). Supercriticalfluids in separation science - the dreams, the reality and the future (R.M.Smith). Recent developments in microcolumn liquid chromatography (J.P.C.Vissers). Developments in sample preparation and separation techniques forthe determination of inorganic ions by ion chromatography and capillaryelectrophoresis (P.R. Haddad et al.). State-of-the-art in liquidchromatography-mass spectrometry (W.M.A. Niessen). Liquidchromatography-nuclear magnetic resonance spectroscopy (K. Albert). Liquidchromatography-Fourier-transform infrared spectrometry (G.W. Somsen etal.). Liquid chromatography-inductively coupled plasma mass spectrometry(K.L. Sutton, J.A. Caruso). Programmed temperature vaporiser-basedinjection in capillary gas chromatography (W. Engewald et al.). On-linecombination of aqueous-sample preparation and capillary gas chromatography(J.J. Vreuls et al.). High-speed gas chromatography: an overview of variousconcepts (C.A. Cramers et al.). Comprehensive two-dimensional gaschromatography: a hyphenated method with strong coupling between the twodimensions (J.B. Phillips, J. Beens). Gas chromatography with spectroscopicdetectors (N. Ragunathan et al.). Planar chromatography at the turn of thecentury (C.F. Poole). The state of the art in thin-layerchromatography-mass spectrometry: a critical appraisal (I.D. Wilson).Overview of capillary electrophoresis and capillary electrochromatography(K.D. Altria). Electrokinetic chromatography (J.P. Quirino, S. Terabe).Coupling of biological sample handling and capillary electrophoresis (J.R.Veraart et al.). Analysis of DNA adducts using high-performance separationtechniques coupled to electrospray ionization mass spectrometry (C.L.Andrews et al.). Author index. Subject index.
Hardbound
ISBN:0-444-50190-8540 pages
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Product Description:
Today, we all know that the combination of a conventional injection procedure, a single analytical column and a selective detector often does not suffice to recognize and quantify all analytes of interest in a sample. During the eighties, the use of multidimensional approaches slowly began to make headway to help solve the many, and often complex, problems concerning the provisional identification, or confirmation of the presence, of analytes of interest, the design of separation systems with a considerably improved separation efficiency, and the generally felt need to incorporate the sample preparation in the total analytical procedure.
Two major branches emerged - hyphenation, which is often defined as the on-line combination of a separation technique and a spectroscopic detection device which provides structural information, and coupled-column techniques.
Sometimes hyphenation is used to describe both of these branches, a practice that has also been followed when selecting the title of the present volume.
Gradually the glamour of hyphenation began to be recognised, and the hype and fascination were born.
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