Average Reviews:
(More customer reviews)HPLC has become one of the most widely applied chemical analytical techniques in the pharmaceutical industry.Dr Dong's book, Modern HPLC for Practicing Scientists, provides excellent source of information and knowledge for both beginners and highly experienced professionals who utilize this analytical tool.Chapter 1 presents an overview of chromatographic principles while the 2nd chapter deals with fundamental aspects of HPLC and considerations that enhance efficient separation. In chapter 3, Dr. Dong discusses the chromatographic column both from theoretical perspectives and applications. This is very valuable to practicing scientists.
In Chapter 4, the book provides a concise overview of HPLC instrumentation, operating principles as well as recent advances in instrumentation such as Waters Acquity UPLCTM (Chapter 11).A lot of information is provided on practical issues associated with the use of HPLC systems and the pictures and illustrations make their understanding much easier.
Chapter 5 provides a hands-on approach to HPLC analysis including mobile phase preparation and parameter optimization. This is a great chapter for a novel analyst who is often saddled with numerous options on the choice of HPLC parameters. Dr. Dong's attention to details makes it possible even for the novice chromatographer to undertake a full HPLC procedure with little or no supervision
Although Chapters 6 and 7 deal with applications in the pharmaceutical, food and environmental industries, the practicing scientist who this text is best suited for, would benefit more by integrating information from these chapters with the fundamental and practical concepts documented in the earlier chapters.
The inclusion of method development and regulatory issues with respect to HPLC techniques and applications in chapters 8 and 9 is particularly commendable. Industrial R & D scientists who are not only challenged to develop and optimize methods but also work within the constraints of regulatory agencies would find these chapters immensely rewarding. These chapters provide hands-on guidance for laboratory scientists in the pharmaceutical and other regulatory industries.
Chapter 10, dealing with troubleshooting is one of the special attributes of this book.This chapter provides quick fix approach to resolving some of the HPLC's often encountered problems. This chapter is bound to save some cost because more often than not, the HPLC analyst tend to vainly envisage and explore more catastrophic problems ignoring the simple remedies that are succinctly documented in Chapter 10.
Overall, Dr. Dong's book is very well written. Each aspect of the text is clearly and succinctly presented, making it easy to understand. The chapter on maintenance and troubleshooting guide (Chapter 11) should be a great asset. Dr. Dong has managed, in a very basic but meticulous manner, to produce an essential text for both the novice and experienced HPLC practitioner in the pharmaceutical industry.
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