Neuroanatomical Tract-Tracing: Molecules, Neurons, and Systems Review

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(More customer reviews)This magnificent volume with a modest title "Neuroanatomical Tract-Tracing 3" by Prof. Zaborszky, Wouterlood and Lanciego, amalgamates into one a prosperous collection of recipes and protocols summarizing methodical wisdom and knowledge from world renowned laboratories and experts in brain science. It gives not only a detailed description of guidelines, protocols and procedures of classical neuro-anatomical methods and tract-tracing techniques but also introduces more recent concepts and tools for structural neuroscience such as viral tract-tracing, computational neuro-anatomy, functional imaging and neuronal network modeling. Each chapter (overall 20) starts with a brief and effective introduction to concept and methodology followed by meticulous recipes and applications illustrated with extensive experimental examples, literature overview and discussions. The clarity and wide scope of topics covered by this volume render it the book of choice for new and established explorers of the brain puzzle.

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The first two editions of this title had a tremendous impact in neuroscience. Between the previous edition in 1989 and today, there has been an explosion of information in the field. These include advances in molecular techniques, such as genomics and proteomics, which have become increasing important in neuroscience. A renaissance in fluorescence has occurred, driven by the development of new probes, new microscopes, live imagers, and computer processing. The introduction of new markers has enormously stimulated the field, moving it from tissue culture to neurophysiology to functional MRI techniques.As with previous editions, this new edition will be welcomed by the graduate students working in the lab who needs fast, complete, up-to-date, and immediately applicable information about techniques, written by acknowledged experts in the field.